Programm of the Workshop Genetic Modification and Cell Genome Analysis (31 of October and 1 of November, IDB RAS)
31 October
Moderators E.A. Vorotelak / G.V. Pavlova
9:00-10:00 Registration of participants
10:00-10:30 М.А. Lagarkova, FRCC PCM, MSU “Approaches to the creation of highly immunogenic personalised oncovaccines”
10:30-11:00 A.K. Shaitan, MSU “From understanding the structure and dynamics of chromatin to the development of epigenetic engineering methods based on dCas-proteins”
11:00-11:30 Y. Vassetzky, Institut Gustave Roussy, Villejuif, France “Targeted modification of 3D genome organization”
11:30-12:00 A. Schwager (Karpukhina), Institut Curie, Paris, France “From 3D organisation to therapy of mantle cell lymphoma”
12:00-12:15 Coffee break / Poster session
12:15-12:40 G.V. Pavlova, INHA & NPh RAS “Molecular and genetic aspects of differentiation therapy of human glioma”
12:40-13:05 E.S. Nikitin, INHA & NPh RAS “Gene therapy of epilepsy using calcium-activated potassium channels”
13:05-13:35 I.V. Lyadova, IDB RAS “In vitro models of human macrophage differentiation using induced pluripotent stem cells”
13:25-13:40 E.E. Voronezhskaya, IDB RAS “Fluorescence imaging of gene expression by hybridisation chain reaction: how to start and what can be obtained from it”
13:40-14:10 Lunch / Poster session
Moderators I.V. Lyadova / A.S. Tsimokha
14:10-14:40 R.A. Romanov, IDB RAS “Can maternal stress change the molecular cellular organisation of the brain of offspring”
14:40-14:55 Y. A. Nasykhova, Research Institute of AGiR named after D.O. Ott “Perspectives of using genetically characterised human biomaterial in reproduction”
14:55-15:10 A.F. Sayfitdinova, RSPU, SPbSU “Development of technologies for the study of DNA cells of preimplantation embryos”
15:10-15:25 E. P. Kalabusheva, IDB RAS “Modulation of YAP/TAZ signalling cascade by genetic modification and application of small molecule inhibitors”
15:25-15:40 M.S. Sabirov, IDB RAS “Influence of serotonin on the activity of transcribed regulatory elements during embryonic development of hypothalamus”
15:40-15:50 A.O. Travina, INC RAS “Transcription of tandem repeats in amphibian gametogenesis”
15:50-16:00 Coffee break / Poster session
16:00-16:25 A.S. Tsimokha, INC RAS “The efficiency of cellular reprogramming depends on the activity of immunoproteasomes”
16:25-16:50 P.I. Semenova, INC RAS “Editing of complex heterozygous mutation by CRISPR/Cas9 method in calcium-sensitive receptor gene in culture of induced human pluripotent stem cells”
16:50-17:15 E.G. Ivashkin, IEE RAS “Modern methods of spatial transcriptomics in developmental biology”
17:15-17:40 Y.Y. Silaeva, IGB RAS “An unexpected lesson of crossing error: embryonically lethal in homozygote Flnc gene mutations successfully compensate each other”
17:40-18:10 Summarising the results of the Young Scientist competition (poster presentations) and awarding the winners
1 November
Workshops
10:00-13:00 M.S. Sabirov, IDB RAS “Introduction to the analysis of RNA sequencing data of individual cells”
OR
11:00-11:30 Coffee break
11:30-13:00 V. Gasanov, IDB RAS “Modification of prokaryote cells, obtaining of progenitor strains, evaluation of recombinant protein expression level”
13:00-14:00 Lunch
14:00-16:00 E.E. Voronezhskaya, E.G. Ivashkin, IDB RAS “Identification of results in HCR reaction in tissues using confocal microscope”
OR
14:00-16:00 O.L. Cherkashina, IDB RAS “Genetic modification of eukaryotic cells: lipofection, assembly of viral particles, transduction”
16:00-16:10 Coffee break
16:10-17:30 A.A. Ryabinin, V.K. Abdyev, IDB RAS “Induction of human pluripotent stem cells: methods of cultivation, state of pluripotency, fundamental and applied significance”
17:30 Ending of Conference